Longtime UK ex-pat journalist Jeremy Wagstaff, who for years was the Wall Street Journal's man in Jakarta and all points SE Asia has a very interesting take on Skype and how it will be transforming.
I see Skype in 2010 being the following:
1) The 10,000 pound gorilla in video communications
2) Dramatically expanding their place in day to day business
3) Making huge forays into Enterprise communications - possibly doing their what Microsoft has never been able to achieve
Lastly, I see more and more Skype in the daily lives of people, with one exception. Mobile. I remain unconvinced that Skype even needs a mobile play. What they need is simply connectivity to the mobile network, and not have to keep the fight going. As mobile becomes more and more IP centric, the mobile path for Skype will become much easier.